Haemophilia and Thrombosis Centre

Haemophilia is a lifelong, inherited bleeding disorder. In haemophilia one of the clotting factor proteins, important for blood clotting, is either partly or completely missing. People with haemophilia take longer than normal to stop bleeding. They may have bled into joints and muscles without having had an injury.

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Arterial thrombosis is a blood clot that develops in an artery. It’s dangerous as it can obstruct or stop the flow of blood to major organs, such as the heart or brain.

If a blood clot narrows one or more of the arteries leading to the heart, muscle pain known as angina can occur.

If a blood clot blocks the arteries leading to part of the heart muscle, it will cause a heart attack. If it blocks an artery in the brain, it will cause a stroke.

Symptoms, therefore, depend on where the blood clot has formed.

Deep vein thrombosis (DVT) is a blood clot that develops within a deep vein in the body, usually in the leg.

Blood clots that develop in a vein are also known as venous thrombosis.

DVT usually occurs in a deep leg vein, a larger vein that runs through the muscles of the calf and the thigh. It can also occur in the pelvis or abdomen.

It can cause pain and swelling in the leg and may lead to complications such as pulmonary embolism. 

DVT and pulmonary embolism together are known as venous thromboembolism (VTE).