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Weight Loss Medications

ORLISTAT

Orlistat (Xenical®) is a licensed medication for weight management in NHS Greater Glasgow & Clyde (NHSGGC). This may be offered to some service users following the completion of the 12 week Lifestyle phase of our programme.

Orlistat reduces the production of the enzymes used to break down dietary fat. It works locally in the stomach and intestine to prevent absorption of approximately 30% of the fat from the food we eat.

Orlistat must be combined with a low fat Structured Meal Plan (SMP). Patients are advised to follow a diet containing 40-50 grams of fat distributed evenly over the day. 

GP’s are responsible for prescribing the medication. In NHSGGC, our local formulary advises that GP’s should prescribe Orlistat on the advice of SWMS. This ensures regular monitoring within the prescribing guidelines and appropriate dietary support is provided.

SEMAGLUTIDE (Wegovy®) and TIRZEPATIDE (Mounjaro®)

Semaglutide (Wegovy®) and Tirzepatide (Mounjaro®) have been approved for use in NHS Scotland to assist diet and exercise weight loss methods.

Wegovy and Mounjaro are not being prescribed in NHSGGC as these medications are not yet on the NHS GGC formulary as there are no established patient pathways.

The weight management prescribing of GLP1s blog is now live on the GGC medicines website

Please feedback on the blog writing process using the following medicine update blog form

NHSGGC is working to develop patient pathways for these medications inline with the Scottish Government Consensus Statement:

If you have any questions about this medication pathway, please view this NHS publication on weight management medications